W140 (trifluoroacetate salt)
Molecular Formula : C16H27N2O4P • C2F3HO2
Formula Weight : 456.4g/mol
Formulation:A crystalline solid
It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8.1,2 W140 (trifluoroacetate salt) is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 µM (2a = W146; 2b = W140 in supplemental material).4 It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.
Storage : -20°C
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