15-Lipoxygenase-2 (human recombinant)

Formulation : PBS, pH 7.4, 1 mM DTT and 20% glycerol
Stability : 6 months
Description :
Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1. Expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues. The protein levels and enzymatic activity of 15-LO-2 are both down-regulated in prostate cancer compared with normal and benign prostate tissues, implicating a possible protective role for 15-LO-2 against tumor formation.
Purity : >95%
Storage : -80°C