PRMT6 Polyclonal Antibody

Stability : 1 year
Formulation:
protein G-purified IgG in 200 µl of PBS containing 0.05% BSA and 0.05% sodium azide
Description :
PRMT6 was identified by searching the human genome for protein arginine methyltransferase (PRMT) family members. PRMT6 is a protein with an approximate molecular weight of 42 kDa consisting of a catalytic core sequence common to other PRMT enzymes. PRMT6 demonstrates type 1 PRMT activity, capable of forming both NG-monomethylarginine and asymmetric NG,NG-dimethylarginine derivatives on recombinant glycine- and arginine-rich substrates. A comparison of substrate specificity reveals that PRMT6 is functionally distinct from two previously characterized type 1 enzymes, PRMT1 and PRMT4. In addition to methylating substrate proteins, PRMT6 displays automethylation activity. GFP-fusion protein expression in the transfected cell lines suggest that PRMT6 localizes in the nucleus. 
Storage : -20°C